INTRODUCTION

PINCURE DSR CAPSULE is a combination of domperidone and pantoprazole which belongs to the group of medicines called prokinetic drugs and proton pump inhibitors respectively. It is used to treat peptic ulcers, gastroesophageal reflux disease (GERD) and reflux esophagitis.

Peptic ulcers are painful sores that develop on the linings of the stomach, esophagus or intestines. It causes severe stomach pain with sensation of flatulence, indigestion, vomiting and fatigue.

GERD is a chronic digestive disease in which the acid from the stomach frequently flows into the esophagus leading to irritation of lining of food pipe. Symptoms include heartburn, chest pain, nausea, sensation of lump in throat and stomach discomfort.

Reflux esophagitis can be defined as the inflammation of the food pipe accompanied with acid reflex.

PINCURE DSR CAPSULE acts by reducing the production of gastric acid. It also speeds up the movement of food from the stomach to the intestines, thereby reducing the signs of nausea, vomiting and acid reflux. Due to these actions, it can also reduce the unpleasant signs of GI tract such as nausea, vomiting, indigestion, burping, bloating, acidity or heartburn.

It should be taken at least 15-30 minutes before meals. During treatment with PINCURE DSR CAPSULE your doctor will closely monitor your kidney functions, liver functions and blood magnesium levels to avoid the risk of unwanted side effects.

Before taking PINCURE DSR CAPSULE inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have any blockage or tears in the gut or have weak bones.

PINCURE DSR CAPSULE is not recommended for use in patients having bleeding from the gut. Consult your doctor before taking PINCURE DSR CAPSULE if you are pregnant or breastfeeding. The most common side effects of taking PINCURE DSR CAPSULE are dryness of mouth, constipation and flatulence. Consult your doctor if any of these side effects both.

You must also inform your doctor immediately if you experience any signs of low magnesium levels in blood (such as tiredness, abnormal muscle movements, dizziness, confusion, disorientation, irregular heartbeat).

USES OF PINCURE DSR CAPSULE

It is used in adults to treat:

• Peptic ulcer
• Gastrointestinal Reflux disease (GERD)
• Reflux esophagitis (inflammation of the esophagus)
• Nausea and Vomiting
• Acidity, Heartburn
• Signs of indigestion (such as burping, bloating)

HOW PINCURE DSR CAPSULE WORKS

PINCURE DSR CAPSULE contains two medicines namely domperidone and Pantoprazole. Domperidone is a prokinetic medicine with anti-emetic properties. It works by blocking the actions of a chemical messenger called dopamine in the gut and across the brain and spinal cord.

This action stimulates the gut, reduces acid reflux and speeds up the movements of food from the stomach into the intestines. It also blocks the transmission of nerve signals between the vomiting centers and brain which reduces the onset of nausea and vomiting.

pantoprarazole is a proton pump inhibitor. It reduces gastric acid secretion by the blocking the actions of a protein membrane called H+K+Atpase (proton pump) present in the lining of the stomach.

By reducing stomach acid production, PINCURE DSR CAPSULE it prevents the worsening of ulcers, heals the existing ulcers and esophageal lesions and provides relief from the unpleasant symptoms of GI tract (such as acidity, bloating, burping and indigestion).

DIRECTIONS FOR USE

Take PINCURE DSR CAPSULE  15-30 minutes before meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking PINCURE DSR CAPSULE unless your doctor advice you to stop.

SIDE EFFECTS OF PINCURE DSR CAPSULE

COMMON

• Benign polyps in the stomach
• Dry mouth

UNCOMMON

• Low sex drive
• Headache, dizziness, drowsiness
• Anxiety, sleeplessness
• Breast enlargement in both men and in women
• Feeling weak
• Fragile bones (risk of bone fracture)
• Nausea or vomiting
• Diarrhea, constipation, stomach pain, flatulence

RARE

Stop taking PINCURE DSR CAPSULE and inform your doctor immediately if you experience any of the following side effects such as:

• Severe allergic reactions (such as skin rash, itching, swelling of the lips, face or body and difficulty in breathing or swallowing)
• Signs of liver problems (yellowing of the skin and eyes, dark urine and tiredness)
• Severe skin reactions (such as redness, blistering, peeling of skin and bleeding in the lips, eyes, mouth, nose and genitals with fever)
• Signs of kidney problem (such as lower back pain, painful urination)
• Signs of low magnesium levels in blood (such as tiredness, abnormal muscle movements, dizziness, confusion, disorientation, irregular heartbeat)
• Skin rashes on sun exposed areas
• Sudden weight loss, looking pale and weak (anemia)
• Signs of bleeding in the gut (such as bloody vomits/stools)
• Chest pain
• Severe, persistent diarrhea